Oxford Healthspan was founded by Leslie Kenny, an Oxford-based entrepreneur born in California and a graduate of Berkeley and Harvard Business School. In her 30s, she was diagnosed with an array of autoimmune conditions and her doctors told her there was no cure and that they could only be managed with strong immunosuppressants. 

This didn’t sit right with her. Coming from a Taiwanese background, she was raised with the mentality that it’s best to work with your body’s innate wisdom to heal itself. On a quest to revive her own health, she went back to school at the Institute for Integrative Nutrition in NYC. Her passion for health optimization grew and her career took an interesting and unexpected turn when she moved to Oxford and began working with Oxford University scientists and doctors. 

At a meeting with a fellow scientist, she learned of a natural compound called spermidine, found in a Japanese fermented soybean dish called natto – scientists were calling it ‘an anti-aging vitamin’. Leslie tried (and struggled) to find natto in the US and spotting the unmet need for an alternative to natto, she decided to bring a highly concentrated spermidine supplement to the US market. With the support of esteemed University of Oxford scientists and doctors she launched Oxford Healthspan with its flagship product, the plant-derived spermidine supplement, Primeadine®. 

The research on spermidine shows it to inhibit 9 of the 12 root causes of aging (known as the Hallmarks of Aging), such as inflammation, gut dysbiosis, and stem cell and mitochondrial dysfunction, and trigger autophagy (cellular renewal).  Studies also revealed it to increase lifespan, enhance hair growth, and improve heart health, memory and cognition. Today, at age 58, Leslie has reversed her autoimmune conditions. 

Spermidine is found in all living things but is most concentrated in sperm (hence the name!), breast milk, and the endosperm of seeds, such as wheat germ. We naturally produce spermidine, but our ability to do so declines with age, impacting our ability to trigger autophagy also. This increases our dietary needs for spermidine and is where food-derived, supplemental sources of spermidine come in handy. 



Oxford Healthspan work with an internationally recognized team of scientists and doctors. They source ingredients in Japan, the purest, most potent and bioavailable raw materials that are consumed by centenarians. These are rigorously lab tested for impurities and efficacy, meeting the high standards of the Japanese Food Association as well as GMP and ISO22000. 

Benefits include healthy aging, enhanced cell renewal, better sleep quality, energy and vitality, healthier hair, skin and nails, improved brain health, memory and cognition, and better gut and heart health! 

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Primeadine® Original is a wholly plant-derived spermidine supplement for healthy aging and activating cellular renewal, or autophagy. Each serving contains 900mg of concentrated Japanese wheat germ extract, providing 1mg of the purest, most bioavailable spermidine. 



Primeadine® GF is a wholly plant-derived, gluten-free spermidine supplement sourced and made in the longevity islands of Okinawa, Japan, home to some of the world’s longest-lived people. Each serving provides 1.2mg of the purest, most bioavailable spermidine and extra autophagy inducers from the unique blend of Okinawan chlorella, Shikuwasa lime, and turmeric. The answer for those who avoid gluten or are Celiac but still want to experience the healthspan-promoting benefits of plant-derived spermidine!  


Get 15% off with my discount code:

Use JANEYLEE as the discount code. GO HERE TO SHOP